ESG Report 2022

6.4.2 Reporting of Adverse Drug Reacions The Group has established effective information The Periodic Safety Update Report is prepared and collection channels for doctors, pharmacists and submitted within the prescribed time limit according patients, and proactively collects information on to the internal Periodic Safety Update Report clinical use, academic literature and holders of submission schedule and annual submission plan. ADRs by means of sales personnel liaising with As for adverse drug reaction events, the Group will medical institutions or drug distributors, publishing record, analyse and handle them in detail, and contact telephone numbers and faxes in the Drug report to the national drug adverse reaction Formulary, establishing a feedback mailbox for supervision information agency or the drug suspected adverse drug reactions on the supervision and management department and the Company's official website, answering and department of public health administration within handling feedback calls on adverse drug reactions the prescribed time according to the impact of the by dedicated staff, and regularly retrieving event. If serious adverse drug reactions or group academic literatures. Information on adverse drug adverse events emerge, the Group will carry out reactions from relevant websites or forums is also drug recall, publish and submit a drug recall collected. summary report to the public to protect the safety In terms of risk identification and control, safety and health of the general public. analysis of adverse reactions of each variation are performed annually to generate analysis reports. 6.5 Sustainable Supply Chain Management Superior supply chain management is the basis for management. Through the implementation of production enterprises to maintain stable and material supplier management procedures, the efficient production. The United Laboratories sees Group maintains a healthy and sustainable supply sustainable operation of the supply chain as a chain system. In terms of contract management, prerequisite for ensuring business operations, and the Group's procurement contracts will enumerate it is also seen as a great opportunity to boost items such as quality requirements of goods, productivity. delivery standards, delivery terms, intellectual property rights, and integrity clauses to guarantee The Group has been persistent in optimizing the the quality of suppliers' supply and lower the legal supply chain system, procurement process, and and social risks of the supply chain. supplier development, supervision, evaluation, and The Group has established a vertical integration of intermediates and active pharmaceutical production and operation model of “pharmaceutical ingredients, and then delivers them to the Group's intermediates - bulk medicines - finished products”. other production sites for the production of bulk Inner Mongolia Company purchases major raw medicines and finished products, which are finally materials for the production of pharmaceutical sold to end users through various channels. Standards for Quality Control of Pharmaceutical Production Measures for the Supervision and Administration of Drug Production Contract Law of the People's Republic of China Measures for the Supervision and Administration of Circulation of Pharmaceuticals Supply Chain Relevant Laws Regulations and Realm 36 Environmental, Social and Governance Report 2022 The United Laboratories International Holdings Limited 6.5.1 Production and Operation Model